Research Applications
Neuroprotection & Cognitive Function
Pinealon has been shown to protect neurons against oxidative stress and improve learning and memory in aged animal models [1].
Gene Expression & Epigenetics
Modulates expression of genes related to apoptosis, differentiation, and metabolic regulation [2].
Aging & Cellular Senescence Studies
Reported to normalize metabolic processes and increase antioxidant enzyme activity in aging tissues [3].
Stress & Ischemia Models
Demonstrated protective effects on neuronal survival in hypoxia and ischemic brain injury models [4].
References
Khavinson V et al. (2004). Neuroprotective Effects of Pinealon in Aging Rats. Bull Exp Biol Med.
https://link.springer.com/article/10.1134/S2079057011040102Korkushko O et al. (2012). Epigenetic Regulation by Short Peptides: Pinealon Effects on Gene Expression. Biogerontology.
https://khavinson.info/assets/files/2012-Arutjunyan.pdfKhavinson V et al. (2011). Antioxidant and Anti-Aging Properties of Pinealon. Adv Gerontol.
https://khavinson.info/assets/files/2011-Khavinson_Ribakova.pdfMalinin VV et al. (2013). Pinealon in Experimental Cerebral Ischemia. Neurochem J.
https://link.springer.com/journal/11064/volumes-and-issues




