CJC-1295+Ipamorelin – 10mg (No DAC)
$ 49.00
All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.
CJC-1295 + Ipamorelin
Research-Grade GH Secretagogue Combination
Tagline: Synergistic GH Release Research
Product Description
CJC-1295 + Ipamorelin is a research combination pairing CJC-1295 (a GHRH analogue) with Ipamorelin (a selective ghrelin receptor agonist) to produce a synergistic stimulation of growth hormone (GH) secretion.
Researchers use this combination to study pulsatile GH release, IGF-1 production, body composition, recovery, and regenerative physiology in preclinical and in vitro models. This combination is especially valuable for exploring both hypothalamic and pituitary contributions to GH regulation.
For Laboratory and Scientific Research Use Only. Not for Human Consumption.
Why Researchers Choose CJC-1295 + Ipamorelin
Dual-Pathway Stimulation: Targets both GHRH and ghrelin receptor pathways for amplified GH release.
Pulsatile GH Secretion: Mimics natural GH pulse patterns, ideal for endocrinology research.
Synergy with IGF-1 Studies: Increases hepatic IGF-1 production for metabolic research.
Reduced Side Effects Profile: Ipamorelin is highly selective, with minimal prolactin/cortisol impact.
Batch Verified: Co-formulated and purity-confirmed for consistent dosing.
Important Note
For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.
| Components | CJC-1295 (Modified GHRH analogue) + Ipamorelin (Selective GHS-R1a agonist) |
| Chemical Formula | CJC-1295: C₁₅₂H₂₅₂N₄₄O₄₂ | Ipamorelin: C₃₈H₄₉N₉O₅ |
| Molecular Mass | CJC-1295: ~3368 Da | Ipamorelin: ~711.9 Da |
| CAS Number | CJC-1295: 863288-34-0 | Ipamorelin: 170851-70-4 |
| Form | Two separate lyophilized peptide vials |
| Shelf Life | 24 months (lyophilized) |
| Intended Use | For preclinical and in vitro research only |
| Storage | -20 °C (dry powder), -80 °C (after reconstitution) |
Research Applications
Growth Hormone Secretion Studies
CJC-1295 increases GHRH receptor activation, while Ipamorelin stimulates ghrelin receptors — together producing greater GH pulses than either alone [1].
IGF-1 Production & Anabolic Signaling
Leads to increased IGF-1 production, supporting protein synthesis and tissue recovery models [2].
Endocrine System Research
Helps investigate hypothalamic-pituitary regulation of GH, somatostatin suppression, and GH feedback loops [3].
Metabolism & Body Composition Studies
Used in models of fat mass reduction, lean mass increase, and metabolic improvement [4].
References
Bowers CY et al. (2004). Synergy Between GHRH Analogues and GHRPs. J Clin Endocrinol Metab.
https://karger.com/nen/article/82/3-4/198/225877/Effects-of-Combined-Long-Term-Treatment-with-aTeichman SL et al. (2006). Pharmacokinetics and Endocrine Effects of CJC-1295. JCEM.
https://academic.oup.com/jcem/article/91/3/799/2843281Kojima M et al. (1999). Discovery of Ghrelin and Its Receptor. Nature.
https://reference.medscape.com/medline/abstract/10604470Svensson J et al. (2003). Growth Hormone Secretagogues and Body Composition. Endocrine.
https://www.researchgate.net/profile/Suzanne-Dickson/publication/12012696_Effects_of_Growth_Hormone_and_Its_Secretagogues_on_Bone/links/0912f5090ed62aaffe000000/Effects-of-Growth-Hormone-and-Its-Secretagogues-on-Bone.pdf
Mechanism of Action (How CJC-1295 + Ipamorelin Works)
GHRH Receptor Activation: CJC-1295 binds GHRH receptors on pituitary somatotrophs, stimulating GH release [Teichman 2006].
Ghrelin Receptor Activation: Ipamorelin binds GHS-R1a, synergistically amplifying GH pulses [Bowers 2004].
Somatostatin Inhibition: Combination reduces inhibitory tone, allowing stronger GH bursts [Bowers 2004].
Increased IGF-1 Production: Elevates circulating IGF-1, promoting anabolism and tissue growth [Svensson 2003].
Pulsatile Secretion: Mimics physiologic GH rhythms, which is critical for proper metabolic and growth signaling [Teichman 2006].
References
Bowers CY et al. (2004). Synergy Between GHRH Analogues and GHRPs. J Clin Endocrinol Metab.
https://karger.com/nen/article/82/3-4/198/225877/Effects-of-Combined-Long-Term-Treatment-with-aTeichman SL et al. (2006). Pharmacokinetics and Endocrine Effects of CJC-1295. JCEM.
https://academic.oup.com/jcem/article/91/3/799/2843281Kojima M et al. (1999). Discovery of Ghrelin and Its Receptor. Nature.
https://reference.medscape.com/medline/abstract/10604470Svensson J et al. (2003). Growth Hormone Secretagogues and Body Composition. Endocrine.
https://www.researchgate.net/profile/Suzanne-Dickson/publication/12012696_Effects_of_Growth_Hormone_and_Its_Secretagogues_on_Bone/links/0912f5090ed62aaffe000000/Effects-of-Growth-Hormone-and-Its-Secretagogues-on-Bone.pdf
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