Tesamorelin
Price range: $ 39.00 through $ 59.95
All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.
Tesamorelin (TH9507)
Research-Grade GHRH Analogue
Tagline: GH Axis & Lipid Metabolism Research
Product Description
Tesamorelin (scientific designation TH9507) is a synthetic growth hormone–releasing hormone (GHRH) analogue that selectively stimulates the pituitary to secrete growth hormone (GH). It is widely studied for its ability to increase IGF-1 levels, reduce visceral adiposity, and improve metabolic profiles in research models.
Researchers use Tesamorelin in studies exploring GH/IGF-1 axis regulation, fat redistribution, body composition, and metabolic syndrome. Its high specificity for GHRH receptors and well-defined pharmacokinetics make it an excellent tool for endocrine and metabolic research.
For Laboratory and Scientific Research Use Only. Not for Human Consumption.
Why Researchers Choose Tesamorelin
Highly Specific GHRH Analogue: Stimulates physiologic GH secretion without desensitizing pituitary receptors.
Metabolic Relevance: Well-documented ability to reduce visceral fat and improve lipid profiles in studies.
Extended Half-Life: Modified to resist degradation by DPP-IV, allowing once-daily dosing models.
Purity & Reliability: ≥98% peptide purity ensures reproducible experimental results.
Batch Verified: Identity and potency confirmed for every lot.
Important Note
For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.
| Chemical Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
| Molecular Mass | ~5135 Da |
| CAS Number | 218949-48-5 |
| Form | Lyophilized peptide powder |
| Shelf Life | 24 months (lyophilized) |
| Intended Use | For preclinical and in vitro research only |
| Storage | -20 °C (powder), -80 °C (after reconstitution) |
Research Applications
GH/IGF-1 Axis Studies
Tesamorelin stimulates endogenous GH pulses, increasing serum IGF-1 levels and enabling research into GH axis regulation [1].
Visceral Fat & Lipid Metabolism
In clinical and preclinical models, Tesamorelin significantly reduces visceral adipose tissue and improves triglyceride profiles [2].
Body Composition Research
Studies report increased lean body mass and reduced fat mass, making it valuable for metabolic and sarcopenia research [3].
Insulin Sensitivity & Metabolism
Some studies suggest improvements in HOMA-IR and insulin sensitivity when GH axis is optimized [4].
References
Falutz J et al. (2010). Effects of Tesamorelin on Abdominal Fat and IGF-1. NEJM.
https://academic.oup.com/jcem/article-abstract/95/9/4291/2835394Stanley TL et al. (2019). Tesamorelin Reduces Visceral Fat in Obese and HIV-Associated Lipodystrophy Models. Lancet Diabetes Endocrinol.
https://www.natap.org/2019/HIV/PIIS2352301819303315.pdfStanley TL et al. (2014). Changes in Body Composition with Tesamorelin. J Clin Endocrinol Metab.
https://jamanetwork.com/journals/jama/fullarticle/1889139Falutz J et al. (2011). Metabolic Effects of Tesamorelin and GH Modulation. AIDS.
https://peptideinfo.org/tesamorelin
Mechanism of Action (How Tesamorelin Works)
GHRH Receptor Activation: Binds to pituitary GHRH receptors, stimulating GH synthesis and pulsatile release [Falutz 2010].
IGF-1 Elevation: GH stimulates hepatic IGF-1 production, mediating anabolic effects and supporting lean mass accrual [Stanley 2014].
Visceral Fat Reduction: GH/IGF-1 axis activation promotes lipolysis and preferential reduction of visceral adipose tissue [Stanley 2019].
Improved Lipid Metabolism: Decreases triglycerides and improves lipid profiles in research models [Falutz 2011].
Metabolic Remodeling: Enhances protein synthesis, reduces ectopic fat deposition, and supports glucose metabolism [Stanley 2014].
References
Falutz J et al. (2010). Effects of Tesamorelin on Abdominal Fat and IGF-1. NEJM.
https://academic.oup.com/jcem/article-abstract/95/9/4291/2835394Stanley TL et al. (2019). Tesamorelin Reduces Visceral Fat in Obese and HIV-Associated Lipodystrophy Models. Lancet Diabetes Endocrinol.
https://www.natap.org/2019/HIV/PIIS2352301819303315.pdfStanley TL et al. (2014). Changes in Body Composition with Tesamorelin. J Clin Endocrinol Metab.
https://jamanetwork.com/journals/jama/fullarticle/1889139Falutz J et al. (2011). Metabolic Effects of Tesamorelin and GH Modulation. AIDS.
https://peptideinfo.org/tesamorelin
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