Ipamorelin
Price range: $ 29.00 through $ 42.00
All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older
Ipamorelin Peptide
Research-Grade GHRP Analogue
Tagline: Selective GH Secretagogue
Product Description
Ipamorelin is a highly selective growth hormone secretagogue (GHRP) that stimulates GH release via activation of ghrelin (GHS-R1a) receptors. Unlike earlier GHRPs (e.g., GHRP-6), Ipamorelin has minimal impact on cortisol or prolactin levels, making it a more targeted research tool.
Researchers use Ipamorelin in preclinical models to study pituitary GH release, IGF-1 production, muscle growth pathways, fat metabolism, and tissue repair mechanisms. Its clean receptor profile and short half-life make it ideal for pulsatile GH secretion research.
For Laboratory and Scientific Research Use Only. Not for Human Consumption.
Why Researchers Choose Ipamorelin
Highly Selective: Minimal effect on ACTH, cortisol, and prolactin.
Potent GH Release: Strong activation of GH pulses in animal models.
Favorable Safety Profile: Reduced off-target endocrine effects compared to GHRP-6 or Hexarelin.
Short-Acting: Allows study of physiological pulsatile GH release.
Batch Verified: Each lot tested for purity, identity, and potency.
Important Note
For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.
| Chemical Formula | C₃₈H₄₉N₉O₅ |
| Molecular Mass | 711.9 Da |
| CAS Number | 170851-70-4 |
| Form | Lyophilized peptide powder |
| Shelf Life | 24 months (lyophilized) |
| Intended Use | For preclinical and in vitro research only |
| Storage | -20 °C (dry powder), -80 °C (after reconstitution) |
Research Applications
GH Secretion Studies
Ipamorelin selectively stimulates GH release from the pituitary, making it valuable for research into pulsatile GH secretion and IGF-1 elevation [1].
Muscle Growth & Recovery
Animal studies indicate increased protein synthesis and support for muscle hypertrophy and recovery [2].
Metabolic Regulation
Ipamorelin has been shown to promote lipolysis and improve body composition in preclinical models [3].
Combination Therapy Research
Frequently studied in combination with CJC-1295 to evaluate synergistic effects on GH and IGF-1 [4].
References
Raun K, Hansen BS, Johansen NL, et al. European Journal of Endocrinology. 1998;139(5):552-561.
https://academic.oup.com/ejendo/article/139/5/552/6748390Svensson J, Lall S, Dickson SL, et al. Journal of Endocrinology. 2000;165(3):569-577.
https://joe.bioscientifica.com/downloadpdf/view/journals/joe/165/3/569.pdfAndersen NB, Malmlöf K, Johansen PB, et al. Growth Hormone & IGF Research. 2001;11(5):266-272.
https://www.sciencedirect.com/journal/growth-hormone-and-igf-research/vol/11/issue/5Penarrubia J, Gálvez M, Pavía J, et al. Journal of Clinical Endocrinology & Metabolism. 1994;79(2):456-461.
Teichman SL, Neale A, Lawrence B, et al. Journal of Clinical Endocrinology & Metabolism. 2006;91(3):799-805.https://academic.oup.com/jcem/article/79/2/456/2650652?utm_source=chatgpt.com
https://academic.oup.com/jcem/article-abstract/91/3/799/2843281
Mechanism of Action (How Ipamorelin Works)
Ghrelin Receptor (GHS-R1a) Activation: Binds selectively to ghrelin receptors in the pituitary and hypothalamus, triggering GH release [Raun 1998].
Increases GH Pulsatility: Produces rapid, dose-dependent GH spikes without significantly altering cortisol or prolactin [Raun 1998].
Stimulates IGF-1 Production: GH pulses result in hepatic IGF-1 synthesis, driving anabolic effects [Svensson 2000].
Promotes Lipolysis: Enhances fat breakdown by increasing GH-dependent hormone-sensitive lipase activity [Malmlof 2001].
Minimal Endocrine Disruption: Selective for GH secretion with low risk of elevating ACTH or prolactin [Raun 1998].
References
Raun K, Hansen BS, Johansen NL, et al. European Journal of Endocrinology. 1998;139(5):552-561.
https://academic.oup.com/ejendo/article/139/5/552/6748390Svensson J, Lall S, Dickson SL, et al. Journal of Endocrinology. 2000;165(3):569-577.
https://joe.bioscientifica.com/downloadpdf/view/journals/joe/165/3/569.pdfAndersen NB, Malmlöf K, Johansen PB, et al. Growth Hormone & IGF Research. 2001;11(5):266-272.
https://www.sciencedirect.com/journal/growth-hormone-and-igf-research/vol/11/issue/5Penarrubia J, Gálvez M, Pavía J, et al. Journal of Clinical Endocrinology & Metabolism. 1994;79(2):456-461.
Teichman SL, Neale A, Lawrence B, et al. Journal of Clinical Endocrinology & Metabolism. 2006;91(3):799-805.https://academic.oup.com/jcem/article/79/2/456/2650652?utm_source=chatgpt.com
https://academic.oup.com/jcem/article-abstract/91/3/799/2843281
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