CJC-1295 (No DAC)
Price range: $ 29.00 through $ 49.00
All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.
CJC-1295 (DAC & Non-DAC)
Research-Grade GHRH Analogue
Tagline: Growth Hormone Research Tool
Product Description
CJC-1295 is a synthetic growth hormone-releasing hormone (GHRH) analogue designed to increase growth hormone (GH) secretion by binding to GHRH receptors in the pituitary. It is available in two forms: CJC-1295 with DAC (Drug Affinity Complex) for prolonged half-life and CJC-1295 without DAC for shorter, more pulsatile GH release.
Researchers use CJC-1295 to study GH/IGF-1 axis regulation, metabolism, and recovery pathways in preclinical models. Its ability to induce sustained GH release makes it an important tool in endocrine and metabolic research.
For Laboratory and Scientific Research Use Only. Not for Human Consumption.
Why Researchers Choose CJC-1295
High Purity: ≥98% purity ensures reproducible experimental results.
Extended Half-Life: DAC version allows weekly dosing models.
Receptor Specificity: Targets GHRH receptors with precision.
Stability: Lyophilized form maintains potency during storage.
Versatile Options: Available with and without DAC for different study designs.
Batch Tested: Identity and purity verified for every lot.
Important Note
For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.
| Chemical Formula | C₁₆₅H₂₇₀N₄₆O₄₆ |
| Molecular Mass | ~3367.9 Da (non-DAC form) |
| CAS Number | 863288-34-0 (DAC version) |
| Form | Lyophilized peptide powder |
| Shelf Life | 24 months (lyophilized) |
| Intended Use | For preclinical and in vitro research only |
| Storage | -20 °C (powder), -80 °C (after reconstitution) |
Research Applications
Growth Hormone Secretion Studies
CJC-1295 is studied for its ability to increase pulsatile GH release and raise circulating IGF-1 levels over time [1].
Metabolism & Fat Oxidation
Research suggests CJC-1295 may enhance fat metabolism and improve body composition in animal models [2].
Anti-Aging and Regeneration
Preclinical research suggests CJC-1295 No DAC may help maintain tissue health and support cellular repair. Its effects on GH signaling have been investigated in aging models for possible roles in preserving muscle mass, supporting skin structure, and promoting recovery in various tissues. [3].
Gut Health and Intenstinal Research
Often studied in conjunction with GHRPs (e.g., Ipamorelin) to evaluate synergistic effects on GH secretion [4].
References
Teichman SL et al. (2006). Prolonged Stimulation of GH and IGF-1 with CJC-1295 in Healthy Adults. Journal of Clinical Endocrinology & Metabolism.
https://academic.oup.com/jcem/article-abstract/91/3/799/2843281Mieritz, M. G. et al. (2009). Body composition and metabolic outcomes after GH analog administration. Hormone Research in Paediatrics, 72(2), 114–122. https://www.sciencedirect.com/science/article/pii/S1096637409000409
Lapira, J. et al. (2008). Age-related GHRH signaling and GH pulsatility. Journal of Neuroendocrinology, 20(9), 1012–1019.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2826.2008.01740.xMayo Clinic Staff. (2005). GH stimulation and GI regeneration: Preclinical overview. PubMed, PMID: 15817669.
https://pubmed.ncbi.nlm.nih.gov/15817669/
Mechanism of Action (How CJC-1295 Works)
GHRH Receptor Activation: Binds to growth hormone–releasing hormone receptors in the anterior pituitary, stimulating GH synthesis and release [Teichman 2006].
Increased GH Pulsatility: DAC modification extends half-life, resulting in sustained GH pulses and higher baseline GH levels [Teichman 2006].
IGF-1 Elevation: Elevated GH stimulates hepatic IGF-1 production, supporting anabolic processes [Lengyel 2008].
Metabolic Effects: Promotes fat utilization and supports lean tissue accrual in preclinical models [Rahim 2010].
Synergistic Potential: Works additively with GHRPs (e.g., Ipamorelin) for amplified GH secretion [Smith 2012].
References
Teichman SL et al. (2006). Prolonged Stimulation of GH and IGF-1 with CJC-1295 in Healthy Adults. Journal of Clinical Endocrinology & Metabolism.
https://academic.oup.com/jcem/article-abstract/91/3/799/2843281Mieritz, M. G. et al. (2009). Body composition and metabolic outcomes after GH analog administration. Hormone Research in Paediatrics, 72(2), 114–122. https://www.sciencedirect.com/science/article/pii/S1096637409000409
Lapira, J. et al. (2008). Age-related GHRH signaling and GH pulsatility. Journal of Neuroendocrinology, 20(9), 1012–1019.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2826.2008.01740.xMayo Clinic Staff. (2005). GH stimulation and GI regeneration: Preclinical overview. PubMed, PMID: 15817669.
https://pubmed.ncbi.nlm.nih.gov/15817669/
Related products
-
-
-
Epithalon
Price range: $ 35.00 through $ 89.00 Select options This product has multiple variants. The options may be chosen on the product page -
BPC157+TB500
Price range: $ 52.00 through $ 79.00 Select options This product has multiple variants. The options may be chosen on the product page