PT-141 – 10mg
$ 37.00
All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.
PT-141 (Bremelanotide) Research Compound
Tagline: Innovative Peptide Research
Product Description
PT-141, scientifically known as Bremelanotide, is a synthetic peptide under investigation for its potential effects on metabolic, vascular, and neuroendocrine pathways. As a research compound, PT-141 has gained attention for its unique mechanism of action, distinct from traditional compounds studied in sexual health, metabolism, and neurological fields.
This compound is intended strictly for laboratory use and scientific research only. Researchers study PT-141 to better understand its molecular properties, signaling effects, and possible relevance in multiple biological processes.
Why Researchers Choose PT-141
High purity levels for reproducible data.
Demonstrated stability under proper storage conditions.
Soluble in standard laboratory solvents for easy handling.
Relevant to diverse fields of peptide and receptor pathway research.
Supplied in lyophilized form for extended shelf life.
Manufactured with strict quality assurance for consistency.
Important Note
For laboratory and scientific research only. Not for human consumption.
| Specification | Information |
|---|---|
| Chemical Formula | C50H68N14O10 |
| Molecular Mass | ~1025.2 g/mol |
| CAS Number | 189691-06-3 |
| Form | Lyophilized powder |
| Shelf Life | Up to 24 months (lyophilized) |
| Intended Use | Laboratory research only |
| Storage | -20°C (long term) |
Research
Metabolism & Energy Balance
PT-141 is studied for its effects on metabolic pathways and energy regulation. Findings suggest it may interact with melanocortin receptors that play roles in appetite and energy balance [1].
Cardiovascular & Vascular Studies
Research indicates PT-141 may influence vascular function by acting on central receptors that affect blood flow regulation [2].
Neurological & Endocrine Pathways
Studies explore how PT-141 engages with the melanocortin system in the brain, a network associated with mood, stress response, and hormonal regulation [3].
Sexual Health Mechanisms
Unlike PDE5 inhibitors, PT-141 acts through neural pathways, making it a distinctive research subject in sexual health and related receptor biology [4].
References
- Effect of bremelanotide on body weight of obese women: Data from two phase 1 randomized controlled trials — examines caloric intake and weight loss in obese women.
https://europepmc.org/article/PMC9314948 Phase I Randomized Placebo-controlled, Double-blind Study of the Safety, Tolerability, and Hemodynamic/Pharmacokinetic Effects of Bremelanotide — study looks at PK + cardiovascular (hemodynamic) effects.
https://www.sciencedirect.com/science/article/pii/S0149291817300565221 Bremelanotide: A Review of its Neurobiology and Treatment Efficacy for Female Sexual Dysfunction — describes neurobiological and receptor biology mechanisms (melanocortin, dopamine etc.).
https://doi.org/10.1016/j.jsxm.2016.11.136Targeting the central melanocortin system for the treatment of metabolic and behavioural disorders (review) — mentions bremelanotide (PT-141) in context of melanocortin receptor agonists, energy balance, appetite regulation etc.
https://www.nature.com/articles/s41574-023-00855-y.pdf
Mechanism of Action (How PT-141 Works)
Binds selectively to melanocortin receptors (MC3R and MC4R) in the brain [1].
Activates signaling pathways that modulate vascular tone and neural activity [2].
Influences central regulation of sexual arousal and metabolic balance [3].
Differs from PDE5 inhibitor pathways, acting directly on central nervous system targets [4].
Demonstrates peptide-specific activation of receptor subtypes, offering unique insights into receptor biology.
References
- Effect of bremelanotide on body weight of obese women: Data from two phase 1 randomized controlled trials — examines caloric intake and weight loss in obese women.
https://europepmc.org/article/PMC9314948 Phase I Randomized Placebo-controlled, Double-blind Study of the Safety, Tolerability, and Hemodynamic/Pharmacokinetic Effects of Bremelanotide — study looks at PK + cardiovascular (hemodynamic) effects.
https://www.sciencedirect.com/science/article/pii/S0149291817300565221 Bremelanotide: A Review of its Neurobiology and Treatment Efficacy for Female Sexual Dysfunction — describes neurobiological and receptor biology mechanisms (melanocortin, dopamine etc.).
https://doi.org/10.1016/j.jsxm.2016.11.136
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