MLT II – 10mg
$ 29.00
All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. Prime Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.
Melanotan II (MT-II)
Research-Grade Melanocortin Analogue
Tagline: Pigmentation, Libido & Energy Balance Research
Product Description
Melanotan II (MT-II) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that acts as a non-selective melanocortin receptor agonist. It is widely used in research to study melanogenesis, sexual behavior, appetite regulation, and energy homeostasis.
Researchers investigate Melanotan II for its MC1R-mediated pigmentation effects, MC3R/MC4R roles in sexual and appetite behaviors, and potential neuroendocrine effects. Its broader receptor activity compared to Melanotan I allows exploration of multiple melanocortin pathways.
For Laboratory and Scientific Research Use Only. Not for Human Consumption.
Why Researchers Choose Melanotan II
Non-Selective MC Agonist: Activates MC1R, MC3R, MC4R, and MC5R for multi-pathway research.
Potent Pigmentation Agent: Induces melanin production more strongly than Melanotan I.
Behavioral Research: Used to study libido, sexual arousal, and energy balance in preclinical models.
Extended Half-Life: More metabolically stable than endogenous α-MSH.
Batch Verified: Each lot tested for purity (≥98%) and potency.
Important Note
For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.
| weight | 10mg |
|---|
| Chemical Formula | C₅₀H₆₉N₁₅O₉ |
| Molecular Mass | ~1024.2 Da |
| CAS Number | 121062-08-6 |
| Form | Lyophilized peptide powder |
| Shelf Life | 24 months (lyophilized) |
| Intended Use | For preclinical and in vitro research only |
| Storage | -20 °C (dry powder), -80 °C (after reconstitution) |
Research Applications
Pigmentation & Photoprotection
MT-II stimulates melanin synthesis in melanocytes, increasing pigmentation and UV resistance in preclinical models [1].
Libido & Sexual Behavior Studies
Research shows MC3R/MC4R activation increases sexual arousal and erectile activity in animal and human studies [2].
Energy Balance & Appetite Regulation
Acts on hypothalamic melanocortin receptors to reduce food intake and regulate energy expenditure [3].
Anti-Inflammatory & Neuroendocrine Effects
Melanocortin activation reduces inflammation and supports stress adaptation studies [4].
References
Hadley ME et al. (1996). Melanotan II and Melanogenesis in Animal Models. Ann NY Acad Sci.
https://link.springer.com/content/pdf/10.1007/0-306-47384-4_25.pdfWessells H et al. (2000). Effect of Melanotan II on Sexual Function in Men. Urology.
https://www.sciencedirect.com/science/article/abs/pii/S0090429500006804Cone RD (2005). Melanocortin System and Energy Homeostasis. Endocr Rev.
https://academic.oup.com/edrv/article-abstract/27/7/736/2355223Getting SJ (2006). Anti-Inflammatory Role of Melanocortins. Pharmacol Ther.
https://www.sciencedirect.com/science/article/pii/S0163725805002809
Mechanism of Action (How Melanotan II Works)
MC1R Activation: Stimulates melanocytes to increase eumelanin production, resulting in skin darkening [Hadley 1996].
MC3R/MC4R Agonism: Activates hypothalamic receptors involved in energy balance and sexual behavior [Cone 2005].
Enhanced cAMP Signaling: Increases intracellular cAMP, leading to activation of melanogenesis-related enzymes [Hadley 1996].
Appetite Suppression: Reduces food intake by influencing hypothalamic feeding circuits [Cone 2005].
Anti-Inflammatory Effects: Inhibits NF-κB signaling and cytokine production, reducing inflammation [Getting 2006].
References
Hadley ME et al. (1996). Melanotan II and Melanogenesis in Animal Models. Ann NY Acad Sci.
https://link.springer.com/content/pdf/10.1007/0-306-47384-4_25.pdfWessells H et al. (2000). Effect of Melanotan II on Sexual Function in Men. Urology.
https://www.sciencedirect.com/science/article/abs/pii/S0090429500006804Cone RD (2005). Melanocortin System and Energy Homeostasis. Endocr Rev.
https://academic.oup.com/edrv/article-abstract/27/7/736/2355223Getting SJ (2006). Anti-Inflammatory Role of Melanocortins. Pharmacol Ther.
https://www.sciencedirect.com/science/article/pii/S0163725805002809
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